Correct segregation of the mitotic chromosomes into daughter cells is a highly regulated process critical to safeguard genome stability. During M phase the spindle assembly checkpoint (SAC) ensures that all kinetochores are correctly attached before its inactivation allows progression into anaphase. Upon SAC inactivation. the anaphase promoting complex/cyclosome (APC/C) E3 ligase ubiq... https://miamistares.shop/product-category/valves/