Abstract Single-cell RNA-seq (scRNA-seq) provides a comprehensive measurement of stochasticity in transcription. but the limitations of the technology have prevented its application to dissect variability in RNA processing events such as splicing. Here. we present BRIE (Bayesian regression for isoform estimation). https://www.kingarte.com/product-category/food-servicetabletop-concession-machinespopcorn-machines/